Job Title: PK/PD Scientist/Sr. Scientist/Principal Scientist (PhD/MS)

Kochi, Chennai and Bengaluru

Job Type: Full-time

Department: Translational Research About ThinkBio.Ai

ThinkBio.Ai® is an AI-first life sciences and healthcare solutions company that helps organizations solve complex scientific and clinical challenges through a combination of deep domain expertise and AI-powered knowledge fusion. ThinkBio.AI is revolutionizing the biopharmaceutical and healthcare fields with AI-powered resources. Our specialized teams—science, clinical, AI, software, and managed services—work together to develop AI-based solutions to help our clients find answers to their toughest questions and to accelerate the application of scientific breakthroughs in the clinic.

Position Summary

We are seeking a highly motivated individual with expertise in preclinical and clinical pharmacokinetic, pharmacodynamic (PK/PD) and bioavailability modeling with passion for translational research.

Key Responsibilities

- Hands-on experience in analyzing and interpreting pharmacokinetic (PK) and pharmacodynamic (PD) data from preclinical studies for clinical translation.
- Support PK/PD assessments, data reviews, and scientific evaluations to support drug development research.
- Is an active user of publicly available PK/PD data with a deep understanding of models used for predicting PK/PD from chemical structure of the drug.
- Work with the team to identify data sources, participate in data validation, quality checks, and maintain the integrity and accuracy of PK/PD datasets.
- Expertise in using PK/PD modeling and statistical tools to support data analysis for internal and commercial projects.
- Closely work with the science and the AI team to set up methods to validate PK/PD models, and their outputs.
- Provide guidance to convert PK/PD concepts, workflows,



and scientific requirements into software features and product functionalities.
- Conduct literature reviews and summarize scientific publications relevant to PK/PD, Clinical Pharmacology, and Drug Development to create an internal knowledge library.
- Prepare technical reports, study summaries, scientific presentations, and supporting documentation.
- Ensure compliance with company SOPs, GCP, and applicable regulatory guidelines.
- Maintain accurate documentation and support audit readiness activities.

Collaboration & Project Management:

- Work closely with cross-functional teams, including disease domain experts, AI and software scientists, and clinicians to enable integration of PK/PD models into integrative solutions.
- Communicate findings effectively through reports, presentations and discussions with internal teams and external collaborators.
- Present work in internal research meetings.
- Contribute to grant applications and funding proposals where relevant.

Qualifications & Experience:

- PhD./MSc in Pharmacy, Pharmacology, Pharmaceutical Sciences, Clinical Pharmacology.
- 3 years (PhD) – 5 years (MSc) hands on experience in a preclinical or clinical PK/PD group preferably in Pharmaceutical companies or small chemistry-focused service companies/CRO.
- Must be part of a PK/PD team working with small molecule therapeutics and/or biologics

4.

Experience in preparing preclinical and/or clinical documents for regulatory reviews





- Broad understanding of drug development and methodologies employed for PK/PD modeling from experimental data.

Required Skills

- Good understanding of Pharmacokinetics (PK), Pharmacodynamics (PD), Clinical Pharmacology, and ADME principles.
- Understanding of clinical research, drug development processes, and clinical trial methodologies and how PK/PD/bioavailability data is used for dose determination
- Ability to analyze and interpret raw PK/PD data to calculate exposure, drug clearance, tissue penetration and other parameters.
- Applying PK/PD knowledge to develop AI-based solutions for pharma and biotech use.
- Strong analytical, problem-solving, and critical-thinking abilities.
- Proficiency in Microsoft Office Suite (Excel, Word, and PowerPoint).
- Good written and verbal communication skills.
- Ability to collaborate effectively within multidisciplinary teams.

Preferred Skills

1.

Experience with PK/PD modeling and simulation/statistical tools such as Phoenix WinNonlin, NONMEM, Monolix, R, SAS, or MATLAB.

- Exposure to life sciences technology platforms, AI/ML applications, or data analytics projects.
- Understanding of biostatistics, data visualization, and quantitative analysis techniques.
- Familiarity with software validation, UAT, or product development activities.
- Knowledge of GCP, ICH Guidelines, and regulatory requirements.

6.

Experience working with cross-functional teams involving Science, Data Science, AI, and Software Engineering functions.

Why Join Us?

- Work at the cutting edge of biomedical research.
- Contribute to groundbreaking disease and drug exposure modeling for improved therapeutic efficacy.
- Collaborate with leading experts in multiple disease domains.
- Competitive salary, perks and career development opportunities.

Interested candidates should submit a cover letter and CV to [email protected] or [email protected]

📌 PK/PD Scientist/Sr. Scientist/Principal Scientist (PhD/MS) (Kerala)
🏢 Feathersoft
📍 Kerala