- Lead medicinal chemistry strategies for the design, synthesis, and optimization of novel drug candidates.
- Execute SAR (Structure-Activity Relationship) strategies to improve potency, selectivity, and overall drug-like properties.
- Drive hit-to-lead and lead optimization efforts across multiple discovery programs.
- Incorporate AI-driven drug design and computational modeling into medicinal chemistry workflow.
- Manage external collaborations with CROs' and academic partners to scale compound synthesis and profiling.
- Partner closely with biology, pharmacology, DMPK, and analytical chemistry to integrate data and advance candidates efficiently
- Analyse experimental results, generate hypotheses, and make data-driven decisions to guide programs.
- Build and mentor a team of medicinal chemists, fostering scientific innovation and Qualified growth.
- Remain hands-on in chemistry when needed,



applying creativity and rigour to overcome key design challenges.

Preferred candidate profile

- PhD in Organic or Medicinal Chemistry (or a related discipline) with 10+ years of industry experience in drug discovery.
- Demonstrated leadership in advancing small molecules or peptides into the clinic.
- Deep expertise in synthetic chemistry, drug design, and SAR optimization.
- Exposure to AI-based drug discovery, computational chemistry, or fragment-based design.
- Solid understanding of DMPK, pharmacology, and safety assessment in early development
- Familiarity with patent strategy and regulatory considerations for small-molecule therapeutics
- Proven ability to manage cross-functional projects and external partnerships
- Excellent communication, leadership, and decision-making skills

📌 Lead - Medicinal Chemist (Secunderabad)
🏢 Alembic Pharmaceuticals
📍 Secunderabad