06 Aug
|
AgileGrid Solutions
|
India
06 Aug
AgileGrid Solutions
India
About The Company Flychem is a leading innovator in the cosmetics and pharmaceutical industries, committed to developing advanced delivery systems that enhance the efficacy and stability of active ingredients. With a focus on research-driven solutions, Flychem integrates cutting-edge science with manufacturing excellence to create high-quality, safe, and effective products.
The company's portfolio includes a diverse range of formulations, from liposomal and nanostructured lipid carriers to complex bioactive systems, serving clients across global markets. Flychem's dedication to innovation, quality, and sustainability positions it as a trusted partner for brands seeking to advance their product offerings through scientific excellence.
About The Role The Senior Scientist at Flychem will play a pivotal role in leading the design, development, and scale-up of liposomal, nanostructured lipid carrier (NLC), and encapsulated active systems. This role involves working on innovative formulations that deliver labile and difficult-to-deliver actives, including liposomal retinaldehyde/retinol, THD ascorbate, copper tripeptide, recombinant collagen, and multi-molecular-weight hyaluronic complexes.
The Senior
Scientist will oversee the entire process from laboratory formulation to pilot and production-scale manufacturing, ensuring the development of robust, stable, and reproducible carrier systems. This position combines hands-on formulation science with process engineering, process optimization, and technology transfer to manufacturing, contributing significantly to Flychem’s product pipeline and technological advancements.
Qualifications The ideal candidate will possess a Master’s degree in Pharmaceutics, Chemistry, Chemical Engineering, Biotechnology, or a related discipline. A Ph.D. in a relevant area is advantageous.
Candidates should have between 4 to 7 years of experience in formulation and process development, particularly with liposomes, NLCs, or other encapsulation/delivery systems. Demonstrable experience in developing stable, effective carrier systems for sensitive actives is essential, along with a strong understanding of scale-up processes and GMP practices. Proven ability to work collaboratively across multidisciplinary teams and a strong foundation in analytical techniques are also required.
Responsibilities
- Design and optimize liposomal, NLC, and encapsulated formulations for sensitive actives such as retinol, retinaldehyde, tetrahexyldecyl ascorbate, bakuchiol, copper tripeptide, ceramides, azelaic and salicylic acid, arbutin, and enzymes, with a focus on stability, encapsulation efficiency, and payload protection.
- Develop and refine manufacturing processes including thin-film hydration, ethanol/solvent injection, high-pressure homogenization, microfluidization, and extrusion; define critical process parameters to ensure consistency and quality.
- Select and justify appropriate lipid and carrier systems, such as lecithin, lysolecithin, phospholipids, and glucosyl ceramide, and characterize resulting dispersions through physical and chemical methods.
- Conduct particle size analysis, polydispersity index, and zeta potential measurements using dynamic light scattering; determine encapsulation efficiency and drug loading via ultrafiltration or centrifugation coupled with HPLC/UPLC assays; assess particle morphology using TEM or cryo-TEM techniques.
- Lead scale-up initiatives from laboratory to pilot and full-scale production, ensuring reproducibility, yield, and quality; prepare detailed process development reports, batch records, and technology transfer documentation.
- Design and interpret stability studies, including those for oxidation- and light-sensitive actives, and establish appropriate storage and packaging conditions.
- Collaborate with QC teams to validate analytical methods for encapsulated systems and work with Production and EHS teams to ensure safe handling of solvents and hazardous materials during scale-up.
- Provide technical mentorship to junior scientists, contribute to project planning, and troubleshoot formulation and process issues as they arise.
Advantages Flychem offers a competitive salary package along with comprehensive benefits including health insurance, paid time off, and opportunities for professional development. The company fosters a collaborative and innovative work environment that encourages continuous learning and growth. Employees have access to state-of-the-art laboratories and resources, facilitating cutting-edge research and development. Flychem also emphasizes work-life balance and recognizes the importance of a supportive workplace culture, making it an ideal place for scientists passionate about advancing cosmetic and pharmaceutical science.
Equal Opportunity
Flychem is an equal opportunity employer. We are committed to creating an inclusive environment where all employees and applicants are treated with respect and fairness. We value diversity and encourage individuals of all backgrounds, experiences, and perspectives to apply. Our hiring practices are designed to promote equality and ensure that every candidate has an equal chance to contribute to our innovative team.
📌 Senior Scientist (India)
🏢 AgileGrid Solutions
📍 India