Role & responsibilities :

- 1. Design and manage Phase I to III clinical trials, focusing on first-in-human cancer studies and dose-escalation strategies.
- 2. Analyze how cancer drugs move through the body (PK) and affect the target tumor (PD) to find the right balance between safety and efficacy.
- 3. Use computer modeling and exposure-response analysis to determine the optimal dose and treatment schedule for cancer patients.
- 4. Partner with translational medicine teams to track biomarkers and confirm that the drug is successfully hitting its cancer target.
- 5. Evaluate drug-drug interactions (DDIs) and manage safety risks when combining different cancer therapies.
- 6. Assess drug mixing, reconstitution, and stability to ensure cancer treatments are physically and chemically compatible when mixed for IV infusion.
- 7. Write and review the clinical pharmacology parts of regulatory documents, such as IND, NDA, and BLA submissions.
- 8. Study how factors like liver or kidney damage, age, and genetics change how oncology drugs work in different patient groups.
- 9. Require an advanced degree ( Pharm.D., or M.D.) in pharmacology or a related science, along with industry experience in oncology drug development.

📌 Clinical Pharmacologist (Jaipur)
🏢 CK Birla Hospital (Rukmani Birla Hospital)
📍 Jaipur