The Senior Scientist leads the design, development, and scale-up of liposomal, nanostructured lipid carrier (NLC), and encapsulated active systems across Flychem's portfolio, including liposomal retinaldehyde/retinol, THD ascorbate, copper tripeptide, recombinant collagen, and multi-molecular-weight hyaluronic complexes. The role owns the path from lab formulation through pilot and production-scale process, delivering robust, stable, and reproducible carrier systems for labile and difficult-to-deliver actives. It combines hands-on formulation science with process engineering and technology transfer to manufacturing.

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Key Responsibilities
- Design and optimise liposomal, NLC, and encapsulated formulations for sensitive actives — retinol, retinaldehyde, tetrahexyldecyl ascorbate, bakuchiol, copper tripeptide, ceramides, azelaic and salicylic acid, arbutin, and enzyme actives — with a focus on stability, encapsulation efficiency, and payload protection.
- Develop and optimise carrier-manufacturing processes: thin-film hydration, ethanol/solvent injection,



high-pressure homogenisation, microfluidisation, and extrusion; define and control critical process parameters.
- Select and justify lipid and carrier systems (lecithin, lysolecithin, phospholipids, glucosyl ceramide) and characterise the resulting dispersions.
- Characterise particle size, polydispersity index, and zeta potential by agile light scattering; determine encapsulation efficiency and drug loading via ultrafiltration/centrifugation coupled with HPLC/UPLC assay; assess morphology (TEM/cryo-TEM) where required.
- Lead scale-up from bench to pilot to production, ensuring reproducibility and yield; author process development reports, batch manufacturing records, and technology-transfer documentation.
- Design and interpret physical and chemical stability studies (including for oxidation- and light-sensitive actives) and define storage and packaging requirements.
- Partner with QC on an

📌 Senior Scientist — Liposomal Formulation (India)
🏢 FlyChem
📍 India