Career Category
Information Systems
Job Description
What you will do
Let’s do this. Let’s change the world. We are seeking a highly qualified and motivated Senior Data Scientist with a strong background in computational biology to join the Bioinformatics Technologies team within Amgen’s Automation, Research Data Systems, Informatics, and AI (ARIA) organization. ARIA is a multidisciplinary group embedded within Amgen’s discovery engine, leveraging advancements in digital technologies for disease modeling and digital modality engineering to accelerate the pipeline from target inception through drug development. Within ARIA, Bioinformatics Technologies serves as an innovation hub for developing, deploying, and applying emerging digital technologies in computational biology to drive the next generation of therapeutic discovery.
Cell surface proteins represent a critical interface between cells and their workplace, and the systematic characterization of the surfaceome is essential for therapeutic discovery. By integrating diverse experimental and computational approaches,
surfaceome analysis enables the identification of novel antigens, quantification of protein density and heterogeneity, assessment of internalization potential, and mapping of cell type–specific signatures. These insights are pivotal for advancing the next generation of targeted and multispecific drug modalities. In this role, you will develop and apply advanced computational and AI/ML methods to analyze and model surfaceome data, build scalable workflows and atlases, and collaborate with experimental teams to ensure computational predictions translate into actionable insights for therapeutic discovery. The successful candidate will possess strong analytical aptitude, deep technical expertise in computational sciences and AI/ML, and a solid understanding of molecular and cellular biology, proven by a track record of innovative and collaborative research.