Role Summary

We are hiring a Lead Bioinformatics Engineer to drive architecture and engineering for an enterprise-scale Multi-Omics & AI platform. This is a systems and platform-building role, focused a production-grade data harmonization engine that transforms fragmented omics data into ML-ready feature stores.

Key Responsibilities
Multi-Omics Data Platform Architecture
Building automated harmonization engine for multi-modal data (genomics, transcriptomics, proteomics, metabolomics)
Develop scalable ETL pipelines to ingest and standardize formats (FASTQ, BAM, VCF, H5AD, MTX, GCT)
Architect ML-ready feature stores using optimized formats (Zarr, Apache Arrow, TileDB)
Define 3-tier data models (Dataset, Sample, Feature) linking clinical and molecular data
Implement ontology mapping using standards (Ensembl, HUGO, NCBI)
Embed batch correction & normalization (e.g., ComBat, Harmony)
Pipeline Engineering & MLOps
Build production-grade pipelines for RNA-seq, WGS, and proteomics
Scale data processing on cloud (AWS preferred: S3, EC2, Batch, Athena)




Implement reproducible workflows using Nextflow / Snakemake + Docker/Singularity
Design high-performance APIs (Python/R) for data access and model consumption
Leverage data lake/lakehouse architectures (Iceberg, Delta Lake)
AI & Data Governance Leadership
Translate biological problems into ML-ready datasets and features
Define data validation, contracts, and quality checks
Implement CI/CD and data quality frameworks (Outstanding Expectations, Pydantic)
Ensure data integrity and prevention of bias/data leakage in AI models

Required Qualifications

Experience
Master?s/PhD in Bioinformatics, Computational Biology, Computer Science, or related field
5+ years? experience in bioinformatics data engineering or platform development
Proven experience building production-grade data platforms / data lakes for ML
Hands-on experience with multi-omics integration (=3 modalities)
Exposure to AI/ML pipelines (deep learning, embeddings, LLMs in bio

📌 DATA SCIENTIST (Bengaluru)
🏢 Happiest Minds Technologies
📍 Bengaluru