Role & responsibilities

FERMENTATION OPERATIONS

Run fermentation plant operations from bench scale to 20 KL at full capacity utilisation, and improve their efficiency.

Apply hands-on expertise in wild-type and recombinant microbial fermentation across multiple commercial products.

Operate and troubleshoot fully automatic, bulk-scale fermenters, with a working understanding of scale-up to the capacity in the pipeline.

Drive process optimisation and standardisation through new protocols and strategies; identify and resolve critical bottlenecks and process gaps.

Own contamination control prevention, detection, and corrective action.

DOWNSTREAM PROCESSING

Own DSP operations end to end — centrifugation, chromatography column purification, membrane separation (UF/MF/TFF), solvent extraction, evaporation and distillation, and crystallisation.

Hold DSP to the same rigour, uptime, and compliance discipline as fermentation, from harvest through to final product release.

Troubleshoot DSP deviations hands-on, and drive root-cause analysis and corrective and preventive action.





PROCESS OPTIMISATION & CONTINUOUS IMPROVEMENT

Implement cost-effective improvements across manufacturing KPIs — product titre, batch throughput, yield and recovery, and overall equipment effectiveness.

Recommend and implement changes to workflow, operations, and equipment that raise production efficiency and reduce cost without compromising quality.

Contribute to annual operating budgets and CAPEX planning for facility expansion, equipment procurement, and process improvements.

QUALITY, COMPLIANCE & DOCUMENTATION

Prepare, validate, and implement SOPs for fermentation, downstream processing, cleaning, and sanitation.

Ensure compliance with cGMP, HACCP, and Valuable Hygiene Practices across all fermentation and DSP operations, keeping records complete and audit-ready.

Act as a Subject Matter Expert in regulatory, quality, and customer audits; support drafting and approval of process and quality

📌 Fermentation Manager (Kochi)
🏢 Synthite
📍 Kochi