Principal Machine Learning Engineer

Role Name: Principal Machine Learning Engineer

Department Name: AI Data Science

Role GCF: 6A

ABOUT THE ROLE

Role Description:

We are seeking a Principal Machine Learning EngineerAmgens most senior individual-contributor leaderto build and scale end-to-end machine-learning and generative-AI solutions for enterprise use cases. Sitting at the intersection of engineering excellence, platform enablement and business impact, you will develop, deploy and monitor modelsclassical ML, deep learning and LLM-based solutionssecurely, responsibly and cost-effectively. Acting as a player-coach, you will define technical standards, shape AI solution strategy, establish reusable patterns and reference architectures, and partner with DevOps, Security, Compliance, Product and business teams to deliver enterprise-grade AI solutions in a regulated workplace.
- Own enterprise AI/ML architecture, engineering standards, APIs, guardrails and reusable patterns across cloud and on-prem environments.




- Build production ML/GenAI solutions and lightweight applications that deliver business-ready insights with performance, reliability and usability in mind.
- Build end-to-end ML pipelinesdata ingestion, feature engineering, training, hyper-parameter optimisation, evaluation, registration and automated promotionusing Kubeflow, SageMaker Pipelines, Open AI SDK or equivalent MLOps stacks.
- Build and maintain full-stack AI applications by integrating model services with lightweight UI components, workflow engines or business-logic layers so insights reach users with sub-second latency.
- Establish observability and operational excellence through SLOs, safe deployment patterns (blue-green/canary, shadow, rollbacks), incident runbooks and production monitoring.
- Lead rigorous evaluation (offline/online, A/B), drift detection, and automated retraining.
- Architect LLM/RAG solutions with prompt management, grounding strategies, safety guardrails, evaluation f

📌 Principal Machine Learning Engineer (Hyderabad)
🏢 Amgen
📍 Hyderabad