CAREER CATEGORY

Clinical

JOB DESCRIPTION

What you will do

Let's do this. Let's change the world. We are seeking a Senior Data Scientist to
join the AI & Data for Engineered Biologics team within Amgen's Large Molecule
Discovery (LMD) organization. In this vital role, you will advance data-driven
prediction and design of fit-for-purpose proteins by developing machine learning
models that connect sequence, structure, biophysical measurements, and
experimental outcomes to biomolecular developability and structural
tractability. Your work will reduce reliance on trial-and-error workflows,
improve the probability of experimental success, and guide construct and
condition selection for large-molecule discovery.

The successful candidate will work in a highly cooperative, multidisciplinary
workplace, partnering with protein scientists, structural biologists and ML
engineers to support decisions from early design through sample generation and
structural characterization.

KEY RESPONSIBILITIES
Develop and apply machine learning models to predict sequence-to-property




relationships.
Develop scalable, reproducible data-processing, feature-generation,
model-training, and evaluation workflows for large-scale biological datasets.
Design, implement and train state-of-the-art foundation models including
protein language models, diffusion models, or other generative approaches
using multimodal biological data.
Develop interpretable and uncertainty-aware modeling approaches that quantify
confidence and support decision-making.
Apply active learning and Bayesian optimization to guide experimental design
and iterative improvement of protein design workflows.
Collaborate cross-functionally with experimental teams to define modeling
objectives, prioritize experiments, and interpret results.
Communicate scientific findings clearly through presentations, written
summaries and discussions with technical and non-technical stakeholders.

What we expect of you

We a

📌 Senior Data Scientist Hyderabad
🏢 AMGEN
📍 Hyderabad