Career Category
Engineering
Job Description
Principal Machine Learning Engineer
Role Name: Principal Machine Learning Engineer
Department Name: AI & Data Science
Role GCF: 6A
Hiring Manager Name: Aman Shah

ABOUT AMGEN
Amgen harnesses the best of biology and technology to fight the world’s toughest diseases, and make people’s lives easier, fuller and longer. We discover, develop, manufacture and deliver innovative medicines to help millions of patients. Amgen helped establish the biotechnology industry more than 40 years ago and remains on the cutting-edge of innovation, using technology and human genetic data to push beyond what’s known today.

ABOUT THE ROLE
Role Description:
We are seeking a Principal Machine Learning Engineer—Amgen’s most senior individual-contributor leader—to build and scale end-to-end machine-learning and generative-AI solutions for enterprise use cases. Sitting at the intersection of engineering excellence, platform enablement and business impact, you will develop, deploy and monitor models—classical ML,



deep learning and LLM-based solutions—securely, responsibly and cost-effectively. Acting as a player-coach, you will define technical standards, shape AI solution strategy, establish reusable patterns and reference architectures, and partner with DevOps, Security, Compliance, Product and business teams to deliver enterprise-grade AI solutions in a regulated workplace.
Roles & Responsibilities:
- Own enterprise AI/ML architecture, engineering standards, APIs, guardrails and reusable patterns across cloud and on-prem environments.
- Build production ML/GenAI solutions and lightweight applications that deliver business-ready insights with performance, reliability and usability in mind.
- Build end-to-end ML pipelines—data ingestion, feature engineering, training, hyper-parameter optimisation, evaluation, registration and automated promotion—using Kubeflow, SageMaker Pipelines, Open AI SDK or equivalent MLOps stacks.
- Build and maintain full-

📌 Principal Machine Learning Engineer (Hyderabad)
🏢 AMGEN
📍 Hyderabad