23 Aug
|
Zydus Hospitals
|
Ahmedabad
23 Aug
Zydus Hospitals
Ahmedabad
Role & responsibilities
Position Summary
The Wet Lab Chief is responsible for the day-to-day technical operation, quality, and safety of the molecular wet laboratory, encompassing nucleic acid extraction, library preparation, NGS sequencing runs, ddPCR, FISH/IHC-adjacent molecular workflows, and related bench processes. The role holds hands-on ownership of pre-analytical, analytical, and post-analytical wet lab workflows and acts as the primary technical bridge between bench operations and the Incharge, ensuring every assay meets NABL/CAP-aligned quality standards, turnaround-time targets, and documentation integrity.
Key Responsibilities
1. Laboratory Operations & Workflow Management
- Oversee end-to-end wet lab workflow: sample receipt, accessioning, aliquoting, block/slide tracking, extraction, library prep, quantification/QC, and sequencing/ddPCR setup.
- Coordinate daily bench scheduling across assays (NGS panels, ddPCR EGFR/BCR-ABL, DPYD genotyping, and emerging IHC-linked molecular workflows) to meet TAT commitments.
- Maintain the block and aliquot tracking system across ZCH and Zydus Main Hospital sites, ensuring chain-of-custody integrity for every specimen.
- Flag and escalate capacity constraints to the Incharge with proposed mitigations.
2. Technical & Assay Ownership
- Serve as the technical lead for library preparation, target enrichment, and sequencing platform operations (Illumina/Ion Torrent or equivalent, as applicable).
- Own ddPCR bench operations, including plate setup, droplet generation, and QC of quantification outputs. Also able to handle pyrosequencing, Sanger sequencing and exome sequencing.
- Support validation and go-live of recent assays in the pipeline including analytical verification and documentation.
- Troubleshoot assay failures, low-yield extractions, and QC flags at the bench level, escalating complex or recurring issues to the Incharge and Reporting Consultant.
3. Quality, Compliance & Documentation
- Implement and enforce
📌 Wet Lab Chief (Ahmedabad)
🏢 Zydus Hospitals
📍 Ahmedabad