24 Aug
|
Zydus Hospitals
|
Ahmedabad
24 Aug
Zydus Hospitals
Ahmedabad
Role & responsibilities
Position Summary
The Wet Lab Chief is responsible for the day-to-day technical operation, quality, and safety of the molecular wet laboratory, encompassing nucleic acid extraction, library preparation, NGS sequencing runs, ddPCR, FISH/IHC-adjacent molecular workflows, and related bench processes. The role holds hands-on ownership of pre-analytical, analytical, and post-analytical wet lab workflows and acts as the primary technical bridge between bench operations and the Incharge, ensuring every assay meets NABL/CAP-aligned quality standards, turnaround-time targets, and documentation integrity.
Key Responsibilities
Laboratory Operations & Workflow Management
Oversee end-to-end wet lab workflow: sample receipt, accessioning, aliquoting, block/slide tracking, extraction, library prep, quantification/QC, and sequencing/ddPCR setup.
Coordinate daily bench scheduling across assays (NGS panels, ddPCR EGFR/BCR-ABL, DPYD genotyping, and emerging IHC-linked molecular workflows) to meet TAT commitments.
Maintain the block and aliquot tracking system across ZCH and Zydus Main Hospital sites, ensuring chain-of-custody integrity for every specimen.
Flag and escalate capacity constraints to the Incharge with proposed mitigations.
Technical & Assay Ownership
Serve as the technical lead for library preparation, target enrichment, and sequencing platform operations (Illumina/Ion Torrent or equivalent, as applicable).
Own ddPCR bench operations, including plate setup, droplet generation, and QC of quantification outputs. Also able to handle pyrosequencing, Sanger sequencing and exome sequencing.
Support validation and go-live of recent assays in the pipeline including analytical verification and documentation.
Troubleshoot assay failures, low-yield extractions, and QC flags at the bench level, escalating complex or recurring issues to the Incharge and Reporting Consultant.
Quality, Compliance & Documentation
Implement and enforce
📌 Wet Lab Chief Ahmedabad
🏢 Zydus Hospitals
📍 Ahmedabad