Location: Ahmedabad, Gujarat

Experience: 2–5 Years

Department: R&D; – Peptide Chemistry

Employment Type: Full time

About the Role

We are looking for a motivated and technically skilled Scientist – Peptide Chemistry with 2–5 years of hands-on experience in peptide synthesis, with strong practical knowledge of peptide chemistry, SPPS, cyclic peptide synthesis, purification, and characterization.

Key Responsibilities

Perform SPPS and solution-phase peptide synthesis as required.

Execute linear and cyclic peptide synthesis using appropriate strategies.

Plan synthesis routes based on sequence, complexity, and desired modifications.

Handle coupling, deprotection, cleavage, and related operations.

Develop and optimize cyclic peptide synthesis and cyclization strategies.

Troubleshoot incomplete coupling, deletion sequences, aggregation, and low yields.

Purify peptides using preparative/reverse-phase HPLC and other suitable techniques.

Analyze peptides using analytical HPLC/UPLC.

Characterize peptides using LC-MS/Mass Spectrometry and relevant analytical techniques.

Interpret analytical data and confirm peptide identity, purity, and molecular weight.

Maintain laboratory records, experimental data, and synthesis documentation.

Prepare technical reports and communicate project progress to the R&D; team.

Follow laboratory safety, quality, and documentation procedures.

Collaborate with analytical, process development, and other R&D; teams.

Required Qualifications

M.Sc./M.Tech./Ph.D. in Organic Chemistry, Medicinal Chemistry, Pharmaceutical Chemistry, Chemistry, or related discipline.





2–5 years of relevant hands-on experience in peptide chemistry/peptide synthesis.

Strong practical experience in SPPS and good understanding of peptide structure, chemistry, and synthesis strategies.

Hands-on experience with cyclic peptide synthesis/cyclization.

Practical experience in peptide purification using preparative HPLC.

Experience with analytical HPLC/UPLC and LC-MS/MS or Mass Spectrometry.

Ability to interpret analytical data and troubleshoot peptide synthesis and purification challenges.

Good laboratory practices and strong attention to experimental details.

Preferred Skills

Experience with Fmoc-based peptide synthesis.

Knowledge of peptide coupling reagents and protecting-group chemistry.

Experience with complex, long, or difficult peptide sequences.

Knowledge of peptide modifications such as N-terminal/C-terminal modifications, labeling, stapling, lipidation, or non-natural amino acids.

Experience with automated peptide synthesizers.

Good problem-solving and troubleshooting skills.

Ability to work independently and within a multidisciplinary R&D; team.

Key Competencies

Peptide Synthesis | SPPS | Cyclic Peptides | Peptide Chemistry | HPLC Purification | RP-HPLC | Analytical HPLC/UPLC | LC-MS | Peptide Characterization | Organic Chemistry | Troubleshooting

What We Offer

Opportunity to work on challenging and innovative peptide chemistry projects.

Exposure to advanced peptide synthesis, purification, and characterization techniques.

Collaborative and research-oriented work environment.

- Opportunities for technical and professional growth.

📌 Research Scientist – Peptide Chemistry (Ahmedabad)
🏢 Aventaa
📍 Ahmedabad