Specialist - Carbohydrate and Glycoscience Process Development (Hyderabad)

Specialist - Carbohydrate and Glycoscience Process Development (Hyderabad)

02 Sep
|
Aurigene Pharmaceutical Services
|
Hyderabad

02 Sep

Aurigene Pharmaceutical Services

Hyderabad

Job Discription : Advanced Carbohydrate & Glycoscience Process Development

? Hyderabad / Bengaluru, India

About the Role

We are looking for an experienced Carbohydrate & Glycoscience Process Development Scientist to lead complex carbohydrate and oligosaccharide projects from early route assessment through process development, scale-up, technology transfer, and manufacturing support.

This is a unique opportunity to work at the forefront of carbohydrate chemistry, synthetic glycans, glycoconjugates, and advanced process development , while collaborating with global customers and mentoring high-performing scientific teams.

Key Responsibilities

Scientific Leadership

- Lead carbohydrate and oligosaccharide development programs from proof-of-concept to commercial manufacturing.
- Design and optimize scalable processes involving glycosylation, protection/deprotection, selective functionalization, azidation, and oligosaccharide assembly.
- Drive troubleshooting, root-cause investigations, and process improvements using analytical and reaction data.

Process Development & Scale-Up
- Develop robust, protected, and commercially viable manufacturing processes.
- Support scale-up activities from laboratory to pilot and manufacturing scale.
- Conduct process safety evaluations and support technology transfer activities.

Customer Engagement
- Act as the scientific lead for customer-facing projects.
- Present project progress, technical recommendations, risks, and mitigation plans.
- Participate in technical discussions, project reviews, site visits, and proposal presentations.

Team & Project Management
- Mentor and guide junior scientists.
- Review experimental strategies, technical reports, and project documentation.
- Coordinate cross-functional activities with Analytical R&D;, Manufacturing, Quality, Engineering, Regulatory, Supply Chain, and Project Management teams.

Innovation & Capability Building
- Explore advanced glycan synthesis approaches, automated glycan assembly,



and high-throughput experimentation.
- Contribute to capability development in glycan characterization, glycoconjugates, and next-generation carbohydrate technologies.
- Conduct literature, patent, and technology assessments to drive innovation.

Required Qualifications

Education

- Ph.D. in Organic Chemistry, Carbohydrate Chemistry, Glycoscience, Medicinal Chemistry, or a related discipline.

Experience
- Proven industry experience in carbohydrate and oligosaccharide synthesis and process development.
- Strong expertise in glycosylation chemistry, stereochemical control, and protecting-group strategies.
- Experience supporting technology transfer, scale-up, and manufacturing operations.

Technical Skills
- Deep understanding of carbohydrate process chemistry and impurity control.
- Hands-on experience with HPLC/UPLC, LC-MS, HRMS, NMR, GC, and KF techniques.
- Knowledge of crystallization, purification, and isolation of complex and highly polar molecules.
- Familiarity with process safety, DoE/QbD principles, and scalable manufacturing processes.

Leadership Skills
- Strong project management and stakeholder management capabilities.
- Excellent scientific writing, presentation, and communication skills.
- Ability to mentor teams and deliver projects in a fast-paced environment.

Preferred Experience
- Glycoconjugate vaccines, synthetic glycans, carbohydrate therapeutics, or carbohydrate-based APIs.
- CRO/CDMO process development environment.
- Publications, patents, or postdoctoral research in carbohydrate chemistry or glycoscience.
- Experience with advanced purification technologies and scalable glycan manufacturing.

What Success Looks Like ✅ Successful delivery of carbohydrate programs from concept to technology transfer

✅ Robust, scalable, and commercially viable manufacturing processes

✅ Strong customer partnerships and repeat business opportunities

✅ Development of scientific talent through mentoring and leadership

✅ Advancement of glycoscience capabilities and innovation platforms

📌 Specialist - Carbohydrate and Glycoscience Process Development (Hyderabad)
🏢 Aurigene Pharmaceutical Services
📍 Hyderabad

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