Junior Chemist - Purification Core ObjectiveTo execute efficient organic compound separation, purification, and isolation from crude reaction mixtures. This role requires hands-on expertise in setting up traditional manual columns and operating automated flash chromatography systems (e.g., Combiflash-Teledyne,Biotage to support R&D; or process development. Key Responsibilities

Preparative Separation: Execute manual column chromatography and Thin Layer Chromatography (TLC) for separating complex chemical mixtures.

Automated Chromatography: Operate, program, and maintain automated Flash Chromatography systems.

Method Optimization: Develop gradients and optimize mobile-phase solvents based on TLC retention factor (Rf) analysis to ensure maximum yield and purity.

Sample Preparation: Prepare silica/alumina slurries, dry-load/wet-load samples, and pack columns uniformly to prevent cracking or channeling.

Fraction Management: Collect and analyze eluted fractions using TLC, UV visualization,



or analytical equipment to identify the target product.

Solvent Recovery: Safely operate rotary evaporators to recover solvents and concentrate purified compounds.

Documentation: Maintain detailed, compliant laboratory notebooks and logbooks for all purification runs.

Lab Safety: Adhere to safety protocols, including the handling of hazardous chemicals and proper disposal of solid and liquid waste.

Essential Qualifications

Education: B.Sc. in Chemistry.

Skills: Strong fundamental understanding of compound polarity, adsorption/partition principles, and solvent properties.

Personal Attributes

Meticulous attention to detail and a high level of patience (vital for packing columns).

Robust visual acuity for identifying color bands and spotting TLC plates.

Pay: ₹7,000.00 - ₹7,500.00 per month

Work Location: In person

📌 Junior Chemist Intern (Navi Mumbai)
🏢 SynSmart
📍 Navi Mumbai