Job Description

Job Purpose:

Hands-on experience in R&D;, pilot-scale and plant-scale manufacturing batches, with a solid understanding of organic chemistry, reaction optimization, process development, scale-up, purification, analytical interpretation, and GMP manufacturing practices.

The role involves developing and optimizing chemical processes from laboratory scale through pilot/plant scale, troubleshooting process issues, improving yield and purity, and supporting technology transfer and manufacturing activities.

Key Responsibilities:

1. Process & Product Development
- Develop, optimize, and establish robust chemical processes for pharmaceutical, API, specialty chemical, and fine chemical products.
- Perform reaction route scouting, process optimization, and laboratory experimentation.
- Optimize critical process parameters such as temperature, time, reagent/solvent quantity, concentration, pH, addition rate, agitation, and reaction conditions.
- Evaluate process efficiency with respect to yield, purity, selectivity, cycle time, solvent consumption, and scalability.




- Identify and troubleshoot process-related issues during development and scale-up.

2. R&D; and Scale-Up Activities:
- Plan and execute laboratory R&D; batches and process optimization experiments.
- Demonstrate successful transition from gram scale to kilogram/pilot scale and plant scale.
- Participate in pilot and commercial manufacturing batches and provide technical support during execution.
- Monitor process performance during scale-up and identify potential scale-dependent issues.
- Support process validation, process improvement, and troubleshooting activities.

3. Purification & Isolation:
- Hands-on experience in various purification and isolation techniques, including: Crystallization / precipitation, Fractional / vacuum distillation, Column chromatography, Impurity purge and control strategies
- The candidate should be able to select and optimize suitable purification technology based

📌 Research and Development Executive (Gulbarga)
🏢 Manipal Specialty Chemicals Private
📍 Gulbarga