14 Sep
|
Manipal Specialty Chemicals Private
|
Karnataka
14 Sep
Manipal Specialty Chemicals Private
Karnataka
Job DescriptionJob Description
NJob Purpose:
NHands-on experience in R&D;, pilot-scale and plant-scale manufacturing batches, with a solid understanding of organic chemistry, reaction optimization, process development, scale-up, purification, analytical interpretation, and GMP manufacturing practices.
NThe role involves developing and optimizing chemical processes from laboratory scale through pilot/plant scale, troubleshooting process issues, improving yield and purity, and supporting technology transfer and manufacturing activities.
NKey Responsibilities:
N1. Process & Product Development
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- Develop, optimize, and establish robust chemical processes for pharmaceutical, API, specialty chemical, and fine chemical products. N
- Perform reaction route scouting, process optimization, and laboratory experimentation. N
- Optimize critical process parameters such as temperature, time, reagent/solvent quantity, concentration, pH, addition rate, agitation, and reaction conditions. N
- Evaluate process efficiency with respect to yield, purity, selectivity, cycle time,
solvent consumption, and scalability. N
- Identify and troubleshoot process-related issues during development and scale-up. N
n2. R&D; and Scale-Up Activities:
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- Plan and execute laboratory R&D; batches and process optimization experiments. N
- Demonstrate successful transition from gram scale to kilogram/pilot scale and plant scale. N
- Participate in pilot and commercial manufacturing batches and provide technical support during execution. N
- Monitor process performance during scale-up and identify potential scale-dependent issues. N
- Support process validation, process improvement, and troubleshooting activities. N
n3. Purification & Isolation:
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- Hands-on experience in various purification and isolation techniques, including: Crystallization / precipitation, Fractional / vacuum distillation, Column chromatography, Impurity purge and control strategies N
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📌 Hiring: Research And Development Executive (Karnataka)
🏢 Manipal Specialty Chemicals Private
📍 Karnataka