The Senior Scientist leads the design, development, and scale-up of liposomal, nanostructured lipid carrier (NLC), and encapsulated active systems across Flychem's portfolio, including liposomal retinaldehyde/retinol, THD ascorbate, copper tripeptide, recombinant collagen, and multi-molecular-weight hyaluronic complexes. The role owns the path from lab formulation through pilot and production-scale process, delivering robust, reliable, and reproducible carrier systems for labile and difficult-to-deliver actives. It combines hands-on formulation science with process engineering and technology transfer to manufacturing.

Note: Share your CV to [email protected].

Key Responsibilities

- Design and optimise liposomal, NLC, and encapsulated formulations for sensitive actives — retinol, retinaldehyde, tetrahexyldecyl ascorbate, bakuchiol, copper tripeptide, ceramides, azelaic and salicylic acid, arbutin, and enzyme actives — with a focus on stability, encapsulation efficiency, and payload protection. - Develop and optimise carrier-manufacturing processes: thin-film hydration, ethanol/solvent injection, high-pressure homogenisation, microfluidisation, and extrusion; define and control critical process parameters. - Select and justify lipid and carrier systems (lecithin, lysolecithin, phospholipids, glucosyl ceramide) and characterise the resulting dispersions. - Characterise particle size, polydispersity index, and zeta potential by dynamic light scattering; determine encapsulation efficiency and drug loading via ultrafiltration/centrifugation coupled with HPLC/UPLC assay; assess morphology (TEM/cryo-TEM) where required. - Lead scale-up from bench to pilot to production, ensuring reproducibility and yield; author process development reports, batch manufacturing records, and technology-transfer documentation. - Design and interpret physical and chemical stability studies (including for oxidation- and light-sensitive actives) and define storage and packaging requirements.



- Partner with QC on analytical method suitability for encapsulated systems, and with Production/EHS on safe handling of solvents and hazardous inputs during scale-up. - Provide technical guidance to junior scientists and contribute to project planning and troubleshooting.

Required Qualifications

- M.Sc / M.Pharm / M.Tech in Pharmaceutics, Chemistry, Chemical Engineering, Biotechnology, or a related discipline (Ph.D. in a relevant area is an advantage). - 4–7 years of experience in formulation and process development, with demonstrable work on liposomes, NLCs/SLNs, or other encapsulation/delivery systems.

Required Technical Skills

- Liposome / lipid-carrier formulation and the associated unit operations (homogenisation, microfluidisation, thin-film hydration, extrusion). - Colloidal characterisation: DLS (size/PDI), zeta potential, and encapsulation-efficiency determination. - Working knowledge of HPLC/UPLC for assay of encapsulated actives, ideally in coordination with an analytical team. - Formulation of labile actives and design of protective/encapsulated systems. - Scale-up and technology transfer, with sound GMP documentation practice and awareness of cosmetic manufacturing requirements under the Cosmetics Rules, 2020.

Preferred / Nice-to-Have

- Experience in a cosmetic-ingredient, pharmaceutical, or nutraceutical manufacturing environment. - Familiarity with peptide and protein actives (recombinant collagen, copper tripeptide) or fermentation-derived actives. - Exposure to Design of Experiments (DoE) / QbD approaches to process optimisation. - Understanding of regulatory and safety considerations for nano/encapsulated cosmetic ingredients.

Soft Skills & Behavioural Competencies

- Strong problem-solving and a structured, data-driven approach to development. - Clear technical writing and communication across R&D;, QC, and Production. - Ability to manage multiple development projects and timelines. - Mentoring instinct and collaborative working style. - Ownership and rigour in translating lab work into reproducible manufacturing.

How to apply?

You can apply on LinkedIn or share your CV to [email protected].

📌 Senior Scientist — Liposomal Formulation & Process Development (Hyderabad)
🏢 FlyChem
📍 Hyderabad