High Potent APIs (HPAPI):

- Perform hands-on laboratory chemistry activities involving high-potency APIs / potent compounds.

- Execute chemical reactions, work-ups, purification and related laboratory processes.

- Handle HPAPIs in accordance with applicable safety, containment and handling procedures.

- Maintain accurate laboratory records, experimental data and documentation.

- Support process development, optimization and troubleshooting activities.

- Perform analytical sample preparation and coordinate with analytical teams as required.

- Follow established GMP, EHS and laboratory safety requirements.

- Support investigation and resolution of laboratory/process-related issues.

- Where required, support chemistry activities related to ADC and highly potent payloads.

- Work effectively with cross-functional teams including analytical and other chemistry groups.

Organic Chemist:

- Hands-on experience in performing chemical reactions from mg to gram scale independently under scientific guidance

- Strong knowledge of analytical and purification techniques, including NMR, Mass, HPLC, CombiFlash, and column chromatography

- Skilled in handling reaction setups, glassware assemblies, reagent charging, temperature control, and nitrogen operations

- Excellent documentation and data management practices with the ability to follow scientific procedures, patents, and experimental instructions accurately

Peptide Chemist:

- Hands-on expertise in solid-phase and solution-phase peptide synthesis using automated synthesisers like Syro and Liberty CEM

- Strong experience in peptide purification, characterisation, and analytical techniques, including HPLC, LCMS, and MS

- Capable of independently handling medium- to large-scale peptide synthesis (1 g to 1 kg scale) with troubleshooting abilities

- Skilled in laboratory operations, equipment maintenance, SHE compliance,



literature review, and accurate experimental documentation

Scaleup Chemist:

- Experience in process R&D;, scale-up synthesis, and purification from gm to kg scale

- Skilled in handling 50L/100L GLR assemblies and basic technology transfer activities

- Proficient in 1H NMR, HPLC, and LCMS interpretation

- Strong project execution and team collaboration skills

Antibody Drug Conjugation Chemist (ADC)

- Synthesis and purification of complex antibody drug conjugate (ADC) molecules

- Synthesis of different types of linkers – using natural and unnatural amino acids, PEGs

- Synthesis of highly potent drug molecules – payloads

- Purification of complex and large molecules by flash column and HPLC

- Handling various type chemistry with different payloads

- Interpretation and characterisation of higher molecular weight compounds

Principal Scientist;

- PhD/MSc in Organic Chemistry / Medicinal Chemistry or related field.

- Strong experience in CRO/CDMO research environment.

- Proven team management experience with exposure to handling multiple projects.

- Excellent communication and client-facing skills.

- Ability to drive productivity, scientific excellence, and team development.

Organic Chemist:

- Master’s in Organic Chemistry with 1-3 years of experience in the CRO Industry

Solid organisational, project management and problem-solving skills with impeccable multi-tasking abilities.

- Proactive, highly motivated with a "can do" attitude

- Exceptional interpersonal skills.

Peptide/Scaleup/Antibody Drug Conjugation (ADC) Chemist:

- Master’s in Organic Chemistry with a minimum of 2 years and a maximum of 6 years of experience in the CRO/API Industry

- Adherence to safe practices and procedures

- Contribution to the development of safety protocols and systems

- Must be able to prioritize and organize work responsibilities in order to meet deadlines

📌 Research Associate/Senior Research Associate - High Potent APIs (HPAPI)/Organic/Antibody Drug Conjugation (ADC)
🏢 o2h Group
📍 Ahmedabad