Sr. Scientist is responsible for the planning and execution (wherever applicable) of downstream-related multiple projects with moderate supervision. The individual will report to Sr.

Principal

Scientist level and above and can have a reporting of few team members. the person has to work as downstream subject matter expert for one or more individual project.

What You Will Do:
Sr. Scientist is responsible for but not limited to
Planning and execution of Downstream Process activities for mammalian and/ or microbial products/recombinant protein along with team member under supervision of manager for multiple projects.
to perform day to day planning of activities to be done by the team reporting to him/her, data interpretation in coordination with the reporting manager.
Prepare and or review presentations of the DSP data and discuss in the respective project team meetings.
Attending and representing department in internal and external (wherever applicable) meetings.
Review/drafting of documentation activities like preparation of study protocols, development reports, BPR, SOP, tech transfer documents etc.
Involve in troubleshooting of technical problems encountered at manufacturing post tech transfer.




Responsible for Cross-functional communication with internal and external vendors/clients for technical queries in consultation with reporting manager
Protein purification process development expertise and hands on experience with troubleshooting ability (Chromatography, Depth filtration, Centrifugation, UFDF, sterile filtration etc.) in mammalian/microbial expressed antibodies and/or therapeutic proteins.
Experience in Process characterization using DoE Based process development
Hands on experience on data analytics using different statistical tools will be added advantage.
Experience of Scale up/ Down, Technology Transfer (TT) activities and virus clearance (VCS) studies.
Involve in upkeeping the Lab in running state from equipment and compliance aspect. [Setup, operation, troubleshooting and routine maintenance of purification equipment’s (Chromatography system, pH/ conductivity meter, UFDF system etc)]
Awareness of the domestic and regulatory requirements (CDSCO, EMA, US-FDA, etc.)
Proficiency about awareness in protein analytical data interpretation and linkage with process parameters is an added advantage.

📌 Sr Scientist Purification Process Downstream Biosimilar Pune (India)
🏢 Enzene Biosciences
📍 India