Role & responsibilities

Executive / Senior Executive / Assistant Manager / Junior Manager

Company: MSN Laboratories Pvt. Ltd.
Department: Formulation Research & Development (FR&D;)
Function: Oral Solid Dosage (OSD)
Experience: 28 Years
Qualification: M.Pharm / B.Pharm in Pharmaceutics, Industrial Pharmacy, Pharmaceutical Technology, or related specialization

Position Summary

The position is responsible for execution and/or leadership of Oral Solid Dosage (OSD) formulation development activities, including pre-formulation, prototype development, formulation optimization, process development, scale-up, exhibit/registration batches, stability studies, troubleshooting, and technology transfer.

The candidate will work closely with Analytical R&D;, IPQA, Production, QC, Regulatory Affairs, Packaging, and other cross-functional teams to ensure timely development of robust, scalable, and regulatory-compliant formulations.

Key Responsibilities

1. Pre-Formulation & Product Development

- Conduct pre-formulation studies for APIs and excipients, including:
- Solubility and pKa
- Particle size and morphology
- Bulk/tapped density
- Flow properties
- Compressibility




- Polymorphism/solid-state characteristics
- Drug–excipient compatibility

- Evaluate API characteristics and identify formulation challenges.
- Select appropriate excipients based on functionality, compatibility, product performance, and regulatory requirements.
- Develop formulation prototypes based on the QTPP and target product profile.
- Develop and optimize immediate-release and, where applicable, modified-release OSD formulations.

2. Formulation Development

- Plan and execute formulation trials for tablets and capsules.
- Develop formulations using appropriate manufacturing approaches such as:
- Direct compression
- Dry granulation
- Wet granulation
- Fluid-bed granulation
- Pellet/multiparticulate technology, where applicable

- Optimize formulation variables to achieve desired CQAs such as:

- Assay
- Content uniformity
- Dissolution
- Related substances
- Disintegration
- Hardness
- Friability
- Weight variation

- Conduct comparative dissolution studies and support formulation selection.
- Identify and resolve formulation-related problems during development.

📌 Openings For Formulation Development- Oral Solids (Hyderabad)
🏢 MSN Group
📍 Hyderabad