About AnuBio:

AnuBio is building a multicellular foundation model of the human immune system to transform drug discovery. Our platform, TRAILBLAZER™, creates predictive digital twins of patient immunity—enabling discovery of new therapies without predefined molecular targets.

We operate at the intersection of single-cell biology and AI, with active programs across immuno-oncology, autoimmune disease, and neuroinflammation. Our team includes scientists from leading global institutions, and we are rapidly scaling our data generation engine.

The Role: We are hiring a Scientist with expertise in cancer immunology and single-cell genomics to build experimental programs studying immune responses to therapeutic perturbations. You will design and execute immune-cell perturbation studies, develop and scale our single-cell genomics capabilities, and generate high-quality datasets for predictive modelling and therapeutic discovery. This is a high-autonomy role for someone who combines a strong understanding of immune biology with hands-on experimental experience.

What You'll Do:

- Design and execute immune perturbation experiments using primary human immune cells
- Study immune activation, checkpoint biology and therapeutic response/resistance
- Establish, optimize and scale single-cell RNA-seq workflows
- Own experiments end-to-end, from experimental design & cell perturbation to library prep, QC and sequencing
- Scale workflows to hundreds of samples/conditions and 1M cells
- Troubleshoot and improve assay quality, reproducibility, cost and throughput
- Interpret single-cell data in the context of cancer immunology and therapeutic mechanisms
- Collaborate with ML and computational biology teams on experimental design and predictive modelling




- Build and mentor a growing wet-lab team

Required Qualifications:

- PhD in immunology, cancer biology, molecular biology, genomics or a related field
- Strong experimental background in immunology and/or cancer immunology
- Experience with cell prep (PBMCs, nuclei, fixation methods)
- Hands-on experience with single-cell RNA-seq (Parse Evercode, SPLiT-seq, sci-RNA-seq, etc.)
- Experience with NGS library preparation and QC
- Strong understanding of experimental controls, biological variability and assay design
- Ability to take ownership of experimental programs with minimal supervision

Preferred:

- Direct Experience in tumor immunology, immune checkpoint biology or ICI cancer immunotherapy
- Experience studying responses to cytokines, antibodies or other immune perturbations
- Experience developing genomics assays (NGS, library prep, nucleic acids enzymatic assays)
- Experience with flow cytometry and immune-cell phenotyping
- Familiarity with single-cell analysis tools such as Scanpy or Seurat
- Experience with automation or high-throughput experimental workflows

Who Thrives Here:

- Connects biology, experiments and data to answer meaningful scientific questions
- Takes ownership of complex experiments and troubleshoots independently
- Curious about immune responses to perturbations and therapies and their underlying mechanisms

What We Offer

- High-impact work at the frontier of AI, immunology and therapeutic discovery
- Close collaboration with scientists, founders and ML team
- Market-competitive salary

Apply: Send your CV and a short note to [HIDDEN TEXT] answering:

Tell us about a challenging immune or single-cell experiment you designed or rescued. What went wrong, what did you change, and what did you learn

📌 Scientist Cancer Immunology & Single-Cell Genomics (Chennai)
🏢 AnuBio
📍 Chennai