Senior Scientist / Manager – Formulation R&D;

Department: Research & Development

Function: Formulation R&D;

Reporting to: HOD – Formulation R&D; & QA

Location: ENTOD Pharmaceuticals, Mumbai / R&D; Facility

Role Purpose

ENTOD Pharmaceuticals is looking for a highly motivated and scientifically driven Senior Scientist / Manager – Formulation R&D; to strengthen its formulation development team.

The individual will work directly with the HOD – Formulation R&D; & QA and take ownership of formulation-development projects from concept and feasibility through optimisation, stability, scale-up and technology transfer.

A key component of the position will be to identify, develop and protect intellectual property arising from ENTOD’s R&D; activities, including formulation patents, process innovations and other potentially patentable technologies.

Key Responsibilities

Formulation Development

- Independently plan, design and execute formulation-development projects.
- Develop and optimise ophthalmic and other specialty pharmaceutical formulations.
- Work on conventional as well as complex dosage forms including solutions, suspensions, emulsions and novel drug-delivery systems.
- Undertake pre-formulation studies including solubility, pH, osmolality, excipient compatibility and physicochemical characterisation.
- Apply principles of QbD, DoE and risk-based pharmaceutical development wherever appropriate.
- Troubleshoot challenges involving solubility, stability, precipitation, degradation, preservative compatibility and drug–excipient interactions.

Project Ownership

- Take responsibility for assigned projects from laboratory concept to development-ready formulation.
- Prepare development plans, experimental protocols and project timelines.
- Monitor milestones and proactively identify technical risks and solutions.
- Coordinate with analytical development, microbiology, QA, regulatory, manufacturing and other functions.
- Support scale-up, exhibit/registration batches and technology transfer to manufacturing.

Ophthalmic & Sterile Product Development

- Contribute to the development of sterile ophthalmic formulations, including challenging and poorly soluble molecules.
- Understand critical ophthalmic parameters including ocular tolerability, pH, tonicity, viscosity, particle characteristics,



preservative systems and container-closure considerations.
- Support formulation and development strategies relating to sterility and product stability.

Prior ophthalmic/sterile formulation experience would be strongly preferred.

Intellectual Property & Patents

- Identify patentable innovations arising from formulation development, drug-delivery technologies, manufacturing processes and other R&D; activities.
- Conduct prior-art, scientific literature and patent landscape searches to assess novelty and differentiation.
- Work closely with the HOD, senior management and ENTOD’s patent/IP attorneys to develop appropriate IP protection strategies.
- Prepare invention disclosures and provide scientific and technical inputs for drafting and filing patent applications.
- Coordinate with patent attorneys/IP consultants during patent drafting, filing, examination and prosecution.
- Provide technical responses and experimental evidence required to address patent-office examination reports and objections.
- Assist in designing experiments and generating data specifically required to strengthen patent claims and establish technical advantages.
- Monitor relevant competitor patents and emerging IP within ENTOD’s areas of research.
- Help build and maintain a solid R&D; intellectual-property pipeline and patent portfolio.
- Ensure potentially patentable inventions are appropriately protected before publication, presentation or external disclosure.

Scientific & Technical Leadership

- Act as a key technical support to the HOD – Formulation R&D; & QA.
- Guide and mentor junior formulation scientists and research associates.
- Review experiments, results, development reports and laboratory documentation.
- Encourage scientific thinking, innovation and systematic problem-solving within the R&D; team.
- Remain abreast of advances in formulation science, drug delivery, excipients and pharmaceutical technologies.

Documentation & Regulatory Support





- Maintain high-quality development documentation and laboratory records.
- Prepare formulation-development reports and technical summaries.
- Provide formulation inputs for regulatory dossiers and responses to regulatory queries.
- Ensure development activities are conducted in accordance with applicable quality systems and regulatory expectations.

Candidate Profile

Education: M.Pharm in Pharmaceutics / Pharmaceutical Technology or related discipline.

PhD in Pharmaceutics, Pharmaceutical Sciences, Drug Delivery or a related field would be highly desirable, particularly where combined with strong practical formulation-development experience.

Experience: Approximately 5–10 years of relevant formulation R&D; experience, preferably including ophthalmic, sterile, complex or novel drug-delivery formulations.

Previous involvement in pharmaceutical patent drafting, invention disclosures, prior-art searches or successful patent filings would be a significant advantage.

What We Are Looking For

ENTOD is looking for someone who:

- Is fundamentally a scientist, innovator and problem-solver.
- Can independently take ownership of technically challenging formulation projects.
- Can recognise when an experimental result or formulation approach represents potentially valuable intellectual property.
- Understands both the scientific and practical aspects of converting an invention into a patent application.
- Can work effectively with patent attorneys and translate complex laboratory science into clear technical information for IP filings.
- Can guide younger scientists while remaining hands-on in development.
- Is curious about new molecules, drug-delivery technologies and formulation approaches.
- Wants to help translate scientific ideas into commercially viable and protectable pharmaceutical products.

The Opportunity The successful candidate will work closely with ENTOD’s R&D; leadership on innovative ophthalmic and specialty pharmaceutical products, while playing an important role in strengthening both the company’s formulation-development capabilities and intellectual-property portfolio.

The objective is not simply to develop another formulation — but to create differentiated pharmaceutical technologies, protect the innovation behind them, and ultimately translate them into better medicines.

📌 Senior Scientist / Manager – Formulation R&D (Navi Mumbai)
🏢 Entod Pharmaceuticals
📍 Navi Mumbai