30 Sep
|
Chemco Innovative Chemie
|
Palghar
30 Sep
Chemco Innovative Chemie
Palghar
Company: Chemco Innovative Chemie Pvt. Ltd.
Location: Boisar MIDC, Palghar, Maharashtra
Reporting to: Head – Research & Development
Website: www.chemcoglobal.com
About Chemco
Chemco Innovative Chemie Pvt. Ltd. is a pharmaceutical advanced intermediates and specialty chemicals manufacturing company based in Boisar MIDC, Maharashtra.
With expertise in complex organic synthesis, process development, and scale-up, Chemco specializes in developing and manufacturing advanced pharmaceutical intermediates and Key Starting Materials (KSMs).
As part of our expansion into GMP-aligned manufacturing, we are strengthening our R&D; team to support new product development, process optimization, and commercialization.
Role Overview
We are looking for a hands-on Senior R&D; Chemist to work directly under the R&D; Head and support the complete product development lifecycle—from literature research, route selection, and paper costing to laboratory synthesis, process optimization, piloting, and commercial scale-up.
The ideal candidate should have strong experience in process R&D; within the pharmaceutical intermediates or API industry, with the ability to develop commercially viable and scalable manufacturing processes.
Key Responsibilities
- Literature Research & Process Feasibility
- Conduct scientific literature and patent searches to identify suitable synthetic routes.
- Evaluate routes based on yield, raw material availability, safety, scalability, and commercial viability.
- Prepare reaction schemes, stoichiometric calculations, material balances, and preliminary paper costing.
- Support preliminary Freedom to Operate (FTO) assessments.
2. Laboratory Process Development
- Execute multi-step organic synthesis and independently manage assigned experiments.
- Optimize reaction conditions, yields, purity, and process efficiency.
- Develop and optimize isolation, crystallization, filtration, and drying processes.
- Investigate process-related issues and establish reproducible laboratory procedures.
- Identify opportunities for raw material and manufacturing cost reduction.
3. Piloting & Scale-Up
- Support laboratory-to-pilot and pilot-to-commercial scale-up activities.
- Understand critical scale-up factors, including heat transfer, mixing, reaction kinetics, and process safety.
- Participate in pilot plant trials, process troubleshooting, and yield optimization.
- Coordinate with production teams during technology transfer and initial commercial batches.
4. Documentation & Analytical Support
- Maintain detailed laboratory notebooks, experiment reports, and process development records.
- Prepare process flow diagrams, material balances, batch instructions, and technology transfer documentation.
- Interpret HPLC, GC, FTIR, and other analytical results in coordination with QC.
- Support impurity profiling, in-process controls, and product specification development.
5. Cross-Functional Coordination & Compliance
- Work closely with the R&D; Head, Production, QA/QC, and Procurement teams.
- Ensure compliance with laboratory safety procedures, ISO standards, and applicable GMP/GLP practices.
- Support process risk assessments, deviation investigations, and continuous improvement initiatives.
Candidate Requirements
Education : B.Sc. / M.Sc. in Organic Chemistry or Pharmaceutical Chemistry
Experience: 4–7 years in industrial Process R&D;
Industry: APIs, pharmaceutical intermediates, KSMs, or specialty chemicals
Core Expertise
Organic synthesis, route development, process optimization
Scale-up Experience
Laboratory-to-pilot experience essential; commercial scale-up preferred
Analytical Knowledge
HPLC, GC, FTIR, and impurity profiling
Documentation
Process development reports, material balances, technology transfer
Preferred Experience
- Experience in process R&D; at an API or pharmaceutical intermediate manufacturing company.
- Exposure to nitration, hydrogenation, and other industrial organic transformations.
- Experience preparing preliminary manufacturing costs and optimizing process economics.
- Familiarity with GMP documentation, process safety, and manufacturing operations.
Pay: ₹500,000.00 - ₹600,000.00 per year
Advantages
- Health insurance
- Leave encashment
- Paid sick time
- Paid time off
- Provident Fund
Ability to commute/relocate:
- Palghar, Maharashtra 401506: Reliably commute or planning to relocate before starting work (Required)
Application Question(s):
- Please tell us about your previous experience working in Pharma R&D.;
Education:
- Master's (Required)
Shift availability:
- Day Shift (Required)
- Night Shift (Required)
- Overnight Shift (Required)
Work Location: In person
📌 Senior Research Chemist (Palghar)
🏢 Chemco Innovative Chemie
📍 Palghar