Job description
- Ph.D with Postodoctoral or Masters with 5+ years of hands-on experience in cell-based assay development and troubleshooting skills; ability to handle different plate formats for small molecule screening
- Reporting to senior team leader, work with a group of in vitro assay biologists, learning and coaching group members to improve skills and productivity
- Independently design, conduct, optimize and proactively troubleshoot assays
- Develop, optimize and validate biochemical and cell-based assay platforms for the hit identification, lead optimization and functional characterization of small molecules
- Work on the bench implementing state-of-the-art technologies for the different assay platforms
- Ensure robust and high-quality assays with efficient use of automation and instrumentation
- Data processing, interpretation and presentation to cross functional team members
- Proposing, planning, quoting, tracking reagent needs, usage and executing timelines for each study
- Work closely with other biology groups involved in screening, cell biology,



protein biology and ADME, offering integrated drug discovery support alongside chemistry for multiple client-based projects
- Applicants from across the globe with hands-on experience in small molecule translational biology are welcomed

Job requirements
- Extensive work experience in cell biology and biochemistry techniques
- Good working knowledge of transcription-based studies, targeted protein degradation, target identification and validation
- Cell culture experience and in handling different immortalized cell lines, primary cultures, 3D cultures
- Ability to perform transient transfections and generate secure cell lines
- Good working knowledge of immunoprecipitation and Western blotting for protein analysis, quantification and in studying protein-protein interactions
- Experience in fluorescence microscopy and high-content imagining is an advantage
- Experience in targeted protein degradation, target

📌 Associate Research Scientist/Scientist (Ahmedabad)
🏢 o2h Group
📍 Ahmedabad