• Ph.D with Postodoctoral or Masters with 5+ years of hands-on experience in cell-based assay development and troubleshooting skills; ability to handle different plate formats for small molecule screening

• Reporting to senior team leader, work with a group of in vitro assay biologists, learning and coaching group members to improve skills and productivity

• Independently design, conduct, optimize and proactively troubleshoot assays

• Develop, optimize and validate biochemical and cell-based assay platforms for the hit identification, lead optimization and functional characterization of small molecules

• Work on the bench implementing state-of-the-art technologies for the different assay platforms

• Ensure robust and high-quality assays with efficient use of automation and instrumentation

• Data processing, interpretation and presentation to cross functional team members

• Proposing, planning, quoting, tracking reagent needs, usage and executing timelines for each study

• Work closely with other biology groups involved in screening, cell biology, protein biology and ADME,



offering integrated drug discovery support alongside chemistry for multiple client-based projects

• Applicants from across the globe with hands-on experience in small molecule translational biology are welcomed

• Extensive work experience in cell biology and biochemistry techniques

• Good working knowledge of transcription-based studies, targeted protein degradation, target identification and validation

• Cell culture experience and in handling different immortalized cell lines, primary cultures, 3D cultures

• Ability to perform transient transfections and generate reliable cell lines

• Good working knowledge of immunoprecipitation and Western blotting for protein analysis, quantification and in studying protein-protein interactions

• Experience in fluorescence microscopy and high-content imagining is an advantage

• Experience in targeted protein degradation, target engagement assays

📌 Associate Research Scientist/Scientist (India)
🏢 o2h Group
📍 India