12 Oct
|
Veeda Lifesciences
|
Bengaluru
12 Oct
Veeda Lifesciences
Bengaluru
We are hiring!
Veeda Lifesciences is looking for Analytical Characterization specialists to join our team on-site in Bangalore. with 4 – 7 years of experience working with Biosimilars/Biologics, an in a relevant field, and hands-on expertise in HRMS, CE for biosimilars.
Responsibilities
- Execution of planned experiments/studies using physico-chemical methods.
- Develop advanced LC-MS-based methodologies (ESI, ETD, ECD) for the characterization of protein and peptide products.
- Design and implement integrated analytical strategies by combining chromatography and mass spectrometry techniques. These strategies aim to qualitatively and quantitatively assess product-related variants and impurities. This includes the development of creative sample preparation methods, with a focus on LC-MS, CEX-MS, and SEC-MS, native MS,
HDX as well as the characterization of innovator product batches sourced from various geographical regions to establish a comprehensive quality target profile.
- Lead the development of sophisticated analytical workflows, including multi-attribute methods for post-translational modifications (PTMs), sequence variant analysis, profiling of host cell proteins (HCPs), disulfide bond analysis and shuffling, cell culture metabolite analysis, and glycan profiling.
- Impurity characterization of peptides and comparability assessment with innovator using 2DLC (preferably from Agilent)
- Qualification of LCMS methods and method transfer according to ICH and regulatory guidelines.
Qualifications
- M.Sc ., MTech., or Ph.D.
📌 Senior Analyst (Bengaluru)
🏢 Veeda Lifesciences
📍 Bengaluru