12 Oct
|
Medulla Recruitment Services(Biojobz
|
Mumbai
12 Oct
Medulla Recruitment Services(Biojobz
Mumbai
Lead downstream process development at lab scale (bench centrifuges, small-scale
TFF, lab reactors, etc.) and execute scale-up to pilot plant systems (disk-stack centrifuges, pilot TFF skids, jacketed reactors, spray dryers, etc.)
- Develop, optimize, and validate unit operations across the full DSP train: cell disruption, primary recovery, biotransformation, filtration, and drying
- Design and execute lab-scale DoE studies to establish process design space prior to pilot campaigns
- Author and execute Pilot Batch Records documenting mass balance, unit operation efficiency, yields, and process deviations
- Collect and interpret engineering data (volumetric flow rates, pressure drops, heat transfer, yield losses) to support commercial plant design
- Mentor junior DSP scientists and technicians; provide day-to-day technical direction to the DSP team
- Collaborate closely with upstream fermentation, analytical, and quality teams to ensure process inputs and outputs are aligned
- Ensure all operations comply with safety standards including dust explosion prevention (ATEX/NFPA) and biosafety norms
- Identify and evaluate continuous flow processing approaches where applicable to improve throughput and process economics
MABS and Vaccines - Will not considered, only small molecules experience required.
📌 Downstream Fermentation based API (Mumbai)
🏢 Medulla Recruitment Services(Biojobz
📍 Mumbai