14 Oct
|
Unipath Specialty Laboratory
|
Ahmedabad
14 Oct
Unipath Specialty Laboratory
Ahmedabad
Job Type
Employee
Job Qualification
Master of Science (MSc)
Workplace type
On Site
Required Skills
Skills FFPE tissue processing, sectioning, tumor cellularity assessment, macrodissection, and H&E; slide preparation. DNA/RNA extraction, nucleic acid QC, sample tracking, documentation, and troubleshooting of pre-analytical issues.
Jr. Research Associate
Employee
Job Description
Key Responsibilities:
- Receive and process FFPE tissue blocks, slides, and tissue sections for molecular testing.
- Maintain proper sample accessioning, traceability, and FFPE sample processing logs.
- Perform FFPE sectioning/cutting as per testing requirements, including preparation of unstained sections and H&E-stained; slides.
- Review H&E; slides for tumor presence, tumor cellularity, necrosis, and tissue adequacy in coordination with the pathologist/authorized personnel.
- Select appropriate tumor-rich areas for molecular testing and perform macrodissection where required.
- Perform DNA and RNA extraction from FFPE tissue using validated extraction protocols.
- Assess extracted DNA/RNA for concentration, purity, quality, and quantity using appropriate QC methods.
- Maintain proper documentation of sample receipt, sectioning, extraction, QC results, and sample disposition.
- Identify and document insufficient tissue, low tumor cellularity, poor nucleic acid quality, and other sample-related QC failures.
- Coordinate with the NGS team for sample suitability, library preparation, and downstream testing.
- Ensure proper handling, labeling, storage, and tracking of FFPE blocks, slides, extracted DNA/RNA, and residual samples.
- Follow laboratory SOPs, quality-control requirements, biosafety practices, and sample traceability procedures.
- Maintain and update equipment, reagent, extraction, and sample-processing logs as required.
- Troubleshoot issues related to FFPE sectioning, tissue adequacy, DNA/RNA extraction, and QC failures, and escalate when required.
📌 TECHNICAL | Jr. Research Associate | Clinical Genomics | Ahmedabad - NRL | On site
🏢 Unipath Specialty Laboratory
📍 Ahmedabad