Hello, Greetings from ZettaMine Freelancing Opportunity: We are hiring a POD Lead Computational Protein Design Expert for a short-term Frontier AI Research, Protein Engineering & Generative AI Evaluation initiative..

Location:
India Role: POD Lead Computational Protein Design Expert Educational Eligibility: PhD ( Biology / Biochemistry or Related ) Mode: Remote-Freelancing Duration: 3 Weeks Mandatory Eligibility Criteria Technical Qualification:
• Hands-on experience in computational protein design, protein structure prediction, molecular modeling, or protein engineering.
• Robust understanding of protein folding, protein structure-function relationships, molecular interactions, and sequence-structure optimization.
• Practical experience with tools such as RFdiffusion, ProteinMPNN, AlphaFold, Rosetta, PyMOL, or ChimeraX.
• Strong programming skills in Python and experience developing or executing computational biology workflows.
• Experience working with protein sequence and structure formats, including FASTA, PDB, and mmCIF.
• Ability to evaluate protein structures for structural quality, stability predictions, interface quality, novelty, and biological plausibility.
• Experience designing computational experiments, evaluating scientific results, and identifying model limitations.
• Strong analytical skills and excellent written communication for scientific documentation and technical reporting. Preferred Qualifications
• Experience with generative AI and diffusion-based protein design models.
• Hands-on experience in de novo protein design, protein binder design, motif scaffolding, or enzyme engineering.
• Familiarity with protein-protein docking,



structural refinement, and computational affinity assessment.
• Experience developing scientific benchmarks, scoring rubrics, and automated evaluation pipelines.
• Research publications or open-source contributions in computational biology, structural bioinformatics, or protein engineering.
• Previous experience in AI model evaluation, scientific proof-of-concept development, or research collaborations. What You'll Work On
• Design challenging scientific evaluation tasks involving de novo protein generation, binder design, motif scaffolding, and sequence-structure optimization.
• Develop and execute computational protein design workflows using generative AI models and established protein engineering tools.
• Evaluate AI-generated protein sequences and structures for folding confidence, geometric validity, interface quality, and biological plausibility.
• Develop objective scoring rubrics, reference analyses, and reproducible computational benchmarks.
• Identify model limitations, failure cases, and unrealistic structural predictions.
• Prepare technical reports documenting evaluation findings, scientific assumptions, and limitations.
• Deliver a curated collection of reproducible evaluation tasks and a computational proof-of-concept demonstration. Availability Requirements
• Minimum 40 hours per week.
• At least 4 hours of availability per day.
• Minimum 4 hours of overlap with PST business hours. Employment Type: Contractor assignment (no medical or paid leave). Interested candidates: Please share your updated CV and LinkedIn profile at [email protected]. Thanks & Regards, Karthik K ZettaMine

📌 POD Lead Computational Protein Design Expert (India)
🏢 ZettaMine Labs
📍 India