Job title: General Manager – Information Technology

Company: Enzene Biosciences

Location: Pune (Chakan), Maharashtra – In office

Employment type: Full-time

Seniority level: Director

About Enzene

Enzene Biosciences is a biologics CDMO helping global partners develop and manufacture complex biologics. Our manufacturing sites run to global regulatory standards, and IT sits at the core of how we stay compliant, secure and scalable.

About the Role

We’re looking for a General Manager – IT to lead IT strategy, infrastructure and systems across our pharmaceutical manufacturing operations. You’ll report to the CIO. You’ll keep plant and enterprise systems compliant with GxP, FDA 21 CFR Part 11 and EU Annex 11, and you’ll drive our digital and cybersecurity work across manufacturing locations.

What You’ll Do

- Own IT infrastructure for the manufacturing sites (servers, network, Azure/cloud) and keep production-critical systems highly available
- Lead cybersecurity for OT/IT convergence, covering network segmentation, access control and SIEM/SOC oversight
- Manage compliance audits (FDA, ISO 27001)



and drive CAPA closure on IT-related findings
- Manage vendor relationships, including SOC providers and cloud hosting partners
- Build and lead the IT team (infrastructure, applications, security) across manufacturing locations
- Work with Quality, Regulatory and Operations on digital transformation: automation, data integrity and Part 11 e-signatures
- Own the IT budget, capacity planning and DR/BCP for manufacturing systems
- Report regularly to the CIO on IT performance, risk posture and strategic initiatives

What You Bring

- 12+ years in IT leadership, including 5+ years in pharma or life sciences manufacturing
- Deep knowledge of GxP, Part 11, Annex 11 and data integrity (ALCOA+)
- A strong background in OT security, network segmentation and Azure/hybrid cloud
- Hands-on experience managing IT compliance and the validation documentation lifecycle
- A bachelor’s degree in IT or Engineering. ISO 27001 or PMP certification is a plus

📌 General Manager Information Technology (Chakan)
🏢 Enzene Biosciences
📍 Chakan