12 Nov
|
Agile BioScience
|
Ahmedabad
12 Nov
Agile BioScience
Ahmedabad
Company Description Agile BioScience is a specialized partner in comprehensive protein analysis, supporting biopharmaceutical development from early discovery through regulatory approval and commercialization. The organization provides a full suite of analytical services, including higher-order structural characterization and physicochemical analysis of proteins, monoclonal antibodies, peptides, and antibody-drug conjugates. Its capabilities span amino acid analysis, terminal sequencing, peptide mapping to ICH Q6B guidelines, glycosylation profiling, disulfide bond identification, and intact molecular weight determination. Agile BioScience also utilizes advanced platforms such as icIEF, CE-SDS, RP-HPLC, ion exchange chromatography, DSC, CD, FT-IR, SEC-MALS, SV-AUC, and micro-flow imaging to assess protein structure, stability, and aggregation. Experienced scientists apply state-of-the-art instrumentation and robust methodologies to generate reliable data and meaningful insights for clients worldwide. Role Description The Senior Research Scientist – Protein Characterization will lead and execute complex analytical studies to support protein and biopharmaceutical development projects. This full time, on-site role based in Ahmedabad involves designing experimental plans, performing protein characterization assays, interpreting data, and preparing technical reports and presentations for internal teams and external partners. The individual will oversee method development, optimization,
and validation for structural, physicochemical, and stability assessments of proteins, mAbs, peptides, and ADCs using a range of chromatographic and biophysical techniques. Responsibilities include mentoring junior scientists, ensuring adherence to quality standards and regulatory guidelines, troubleshooting experimental challenges, and maintaining laboratory instrumentation. The role also involves collaborating closely with project managers and clients to understand analytical needs, propose solutions, and deliver timely, high-quality results. Qualifications
• Strong foundation in protein chemistry, biophysics, and biopharmaceutical characterization, with experience across the protein lifecycle from discovery to late-stage development.
• Proficiency in structural and stability characterization techniques (e.g., DSC, CD, FT-IR, SEC-MALS, SV-AUC, micro-flow imaging) for assessing higher-order structure, aggregation, and conformational changes.
• Experience in sequence and composition analysis, including amino acid analysis, N-terminal and C-terminal sequencing, peptide mapping, glycosylation analysis (N-linked and O-linked), disulfide bond mapping, and intact molecular weight determination.
• Ability to design and execute robust experimental studies, perform data analysis and interpretation, and document results in clear technical reports and regulatory-compliant documentation.
• Demonstrated capability to lead
📌 Senior Research Scientist – Protein Characterization (Ahmedabad)
🏢 Agile BioScience
📍 Ahmedabad