Position
- Senior Manager NGS Specialist Location
- Turbhe, Navi Mumbai Experience
- 0-2 years post PhD Educational Background
- PhD in Molecular biology / Genetics / Biotechnology Company Website
- https://haystackanalytics.in/ Who Are We HaystackAnalytics is a HealthTech company creating clinical genomics products, which enable diagnostic labs and hospitals to offer accurate and personalized diagnostics. Supported by India's most respected science agencies (DST, BIRAC, DBT), we created and launched a portfolio of products to offer genomics in infectious diseases. Our genomics based diagnostic solution for Tuberculosis was recognized as one of top innovations supported by BIRAC in the past 10 years, and was launched by the Prime Minister of India in the BIRAC Showcase event in Delhi, 2022. Position Overview The Senior Manager – NGS Specialist will be responsible for providing scientific and technical leadership in client interactions, standardisation and optimisation of nucleic acid extraction and library preparation protocols, and validation of new products and sample types. The role will also involve coordinating with internal and external laboratories to address technical challenges, resolve queries, and ensure consistency and reliability across NGS-based diagnostic workflows.

Key Responsibilities
• Client Discussion and Query Handling
• Lead technical and scientific discussions with clients to understand requirements and address queries related to NGS workflows.
• Provide technical guidance and troubleshooting support for extraction, library preparation, sequencing, and data quality-related issues.
• Coordinate with clients to resolve technical challenges and ensure smooth implementation of NGS workflows.
• Standardisation of Extraction Protocols
• Lead the development, standardisation, and optimisation of DNA/RNA extraction protocols across different sample types.




• Establish standardised workflows to ensure consistency, reproducibility, and quality of extracted nucleic acids.
• Perform quality control of extracted samples using techniques such as qPCR and other relevant molecular biology methods.
• Library Preparation Optimisation
• Lead the development and optimisation of NGS library preparation protocols, including Twist and Illumina workflows.
• Oversee library preparation processes and quality assessments using Bioanalyzer, TapeStation, and other relevant techniques.
• Troubleshoot library preparation challenges and optimise protocols to improve library quality, sequencing performance, and throughput.
• Recent Product / Sample Validation
• Lead validation studies for new products, sample types, and NGS-based diagnostic workflows.
• Design and execute sequencing experiments to evaluate analytical performance, reliability, and workflow efficiency.
• Operate, monitor, and ensure optimal utilisation of NGS sequencing platforms, including Illumina, MGI, and Oxford Nanopore.
• Evaluate sequencing output and implement improvements to enhance overall workflow performance.
• Inter-Laboratory Discussions and Query Resolution
• Lead technical discussions and coordinate with internal and external laboratories to resolve sequencing and workflow-related queries.
• Troubleshoot technical discrepancies and ensure consistency in extraction, library preparation, and sequencing protocols across laboratories.




• Maintain technical documentation, experimental records, validation reports, and standard operating procedures.
• Collaborate with cross-functional teams to improve sequencing workflows and incorporate advancements in NGS technologies. Qualifications
• PhD in Molecular Biology, Microbiology, Genomics, Biotechnology, Bioinformatics, or a related discipline.
• 0-2 years of relevant experience in molecular diagnostics, NGS-based research, genomics, or R&D.;
• Proven expertise in developing, standardising, and optimising nucleic acid extraction and library preparation protocols.
• Experience with NGS sequencing platforms such as Illumina (MiSeq, NextSeq, HiSeq, NovaSeq), MGI, and Oxford Nanopore Technologies (ONT).
• Proficiency in molecular biology techniques, including PCR, qPCR, electrophoresis, and nucleic acid quality assessment.
• Hands-on experience with library quality assessment tools such as Bioanalyzer and TapeStation.
• Experience in troubleshooting and optimising sequencing workflows to improve data quality, library yield, and sequencing throughput.
• Strong understanding of NGS-based product development, analytical validation, and sample validation.
• Experience in infectious disease genomics and molecular diagnostics will be preferred.
• Demonstrated experience in client-facing technical discussions, query resolution, and inter-laboratory coordination.
• Strong leadership, analytical, problem-solving, and decision-making skills.
• Excellent scientific documentation, communication, and stakeholder management skills.
• Ability to independently manage technical projects and collaborate with cross-functional teams.
• Willingness to work in rotational shifts and a 6-day working schedule with a rotational week off.

Skills:
ont,ngs,validation

📌 Senior Manager NGS Specialist (Navi Mumbai)
🏢 HaystackAnalytics
📍 Navi Mumbai