Bangalore

This project is to develop a novel point-of-care device that non-invasively estimates blood rifampicin and bilirubin levels simultaneously, enabling early identification of hepatotoxicity and supporting tailored anti-tubercular therapy in community and programmatic settings. The prototype will be calibrated against gold-standard methods using data from individuals taking rifampicin and patients with hyperbilirubinemia. The expected outcome is a robust, affordable tool for point-of-care therapeutic drug monitoring that can improve cure rates, reduce treatment dropouts, and lower the risk of antimicrobial resistance through dose optimization. Concurrent bilirubin monitoring will facilitate early detection of drug-induced hepatotoxicity, further enhancing safety. Integration of this device into India s National TB Elimination Program and comparable global initiatives could meaningfully improve treatment outcomes and inform future policy decisions.

Salary: Rs 36,400/- p.m

No of Vacancies : One

Key Responsibilities:




- Assist in the day-to-day implementation and coordination of research activities related to the Project.
- Carry out participant recruitment, screening, enrolment, informed consent processes, blood sample collection, sample storage, and data entry in accordance with approved study protocols and ethical guidelines.
- Conduct the handling, timely transportation, and delivery of study samples to reference laboratories, ensuring compliance with temperature requirements, labelling, documentation, and tracking procedures.
- Liaise with clinical departments and medical officers, laboratory teams, research staff, TB DOT center staff, and other relevant stakeholders to facilitate participant recruitment, scheduling, follow-up, and smooth conduct of study procedures.
- Ensure participant welfare throughout the study visit, including managing appointments, facilitating reimbursements, distributing incentives, monitoring participant comfort, and providing

📌 Project Technical Support III- ICMR FIW-TB TDM study Project (Bengaluru)
🏢 St Johns Research Institute Sjri
📍 Bengaluru