Position Title: ARD Characterization Leader NMR Expert
Function: Analytical Research and Development / Molecular Characterization
Location: Hyderabad, Telangana
Reporting To: Head of Analytical R&D; / Characterization Sciences

Role Summary

The ARD Characterization Leader NMR Expert will provide scientific and technical leadership for nuclear magnetic resonance spectroscopy-based characterization across a diverse portfolio, including small molecules, peptides, antibody-drug conjugates, oligonucleotides, linkers, impurities, intermediates, and related complex modalities. The role is responsible for designing, executing, interpreting, and reviewing advanced one-dimensional and two-dimensional NMR experiments to support structure elucidation, identity confirmation, impurity characterization, quantitative analysis, method development, regulatory submissions, and project decision-making.

Key Responsibilities
Lead NMR characterization strategies for small molecules, peptides, ADC payloads, linkers, oligonucleotides, impurities, degradation products, intermediates,



and reference standards.
Design and execute fit-for-purpose NMR experiments including 1D proton, carbon, phosphorus, fluorine, and other relevant nuclei based on molecule class and project need.
Apply advanced 2D NMR techniques such as COSY, TOCSY, HSQC, HMBC, NOESY, ROESY, DOSY, J-resolved, HSQC-TOCSY, and selective experiments for structural assignment and connectivity confirmation.
Interpret complex NMR datasets to support stereochemical assignment, sequence confirmation, conformational analysis, site-specific modification assessment, impurity identification, and structure confirmation.
Develop, optimize, qualify, and validate NMR methods, including quantitative NMR approaches, in alignment with scientific, quality, and regulatory expectations.
Provide expert review of NMR reports, analytical data packages, method documents, investigation summaries, and regulatory-supporting characterization docu

📌 Ar&d Characterization Leader Hyderabad
🏢 Sai Life Sciences
📍 Hyderabad