Engineer and optimize microbial strains using molecular biology, genome editing, strain improvement, and data-driven approaches to develop high-performing and secure production strains.
Key Responsibilities:
- Design and execution of experiments for strain screening, media engineering and process optimization.
- Raw materials chareterization studies
- Bioreactors/fermenters handling on different processes (Batch, fed-batch, Continous and perfusion)
- Indentify the critical process parameters and devise optimal feeding strategies for the enhanced prductivites in the assigned projects
- Perform strain improvement via classical methods (mutation, selection, adaptation).
- Mutants screening for the improved productivity, Prepare cell bank and maintain for QC transfer Samples prepartion of omics studies, respective data anlysis.
- Document experimental data and maintain lab records as per compliance standards.
- Work in collaboration with CFTs for timely execution of the projects and process scale-up.
- Preparation of Standard operating procedures (SOPs), Equipemt operating procedures (EOPs) and timely generation and maintenace of the quality records
- Preparation of process protocls for the pilot plant batches, compilation and analysis of the data from the experiments for better understanding and planning the scale-up activites at the manufacturing site
- Preparation and review of procvess technical report, development report, and MFR on sucessful completion of the Project
- Support to the production team in closing the CAPA, OOS, OOT and deviations
- Ensure compliance with biosafety and regulatory guidelines.
Minimum Requirements
- Masters Degree (MSc, MTech) in Bioprocess Engineering, Biotechnology with a ninimum of 2-3 Years of industrial experience
📌 R&D API fermentation (Bengaluru)
🏢 Biocon
📍 Bengaluru
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