BE Biosol is seeking an experienced Group Lead - Fermentation & Bioprocess Development to lead upstream and downstream process development programs spanning microbial fermentation products and biologics. This role will be instrumental in establishing world-class R&D;, pilot-scale and future commercial manufacturing capabilities for APIs, while supporting the organization's expansion into monoclonal antibodies (mAbs), biosimilars and recombinant biologics.

Key Responsibilities

- Lead bacterial fermentation process development from cell banking, seed development and shake flask studies through pilot-scale fermentation.

- Drive process optimization using advanced understanding of fermenter fluid dynamics, oxygen transfer, mixing, scale-up, metabolism and process engineering principles.

- Apply advanced Design of Experiments (DoE), Quality by Design (QbD), statistical modelling and metabolomics to improve productivity, robustness and process understanding.

- Lead downstream process development, optimization and scale-up including harvest, filtration, TFF and chromatography to achieve target yields, recoveries and impurity profiles.

- Provide scientific leadership for future mAb and biosimilar process development, pilot manufacturing, technology transfer and commercial readiness activities.

- Support establishment of greenfield R&D; and pilot manufacturing facilities, including equipment selection,



process design, commissioning and technology transfer.

- Lead cross-functional teams, mentor scientists and engineers, and drive a culture of innovation, scientific excellence and execution.

Candidate Profile

- PhD / M.Tech / M.Sc. in Biotechnology, Biochemical Engineering, Microbiology, Bioprocess Engineering or related discipline.

- 12+ years of hands-on industrial experience in fermentation, bioprocess development and scale-up.

- Proven expertise in microbial fermentation, process characterization, pilot plant operations and downstream purification.

- Solid knowledge of fluid dynamics, fermentation engineering, metabolomics, PAT tools, DoE and statistical analysis.

- Experience in development and scale-up of APIs or related fermentation-derived products.

- Exposure to mAbs, biosimilars, single-use technologies and biologics manufacturing will be highly preferred.

- Demonstrated success in technology transfer, team leadership, problem-solving and decision-making in a complex R&D; environment.

Key Competencies

- Scientific and technical leadership

- Analytical and critical thinking

- Data-driven decision making

- Hands-on troubleshooting and process optimization

- Team building and stakeholder management

- Greenfield project execution and scale-up expertise

📌 R&D Fermentation - Group Lead (Hyderabad)
🏢 Biological E
📍 Hyderabad